| nanomag® -CLD -spio 초상자성입자 CrossLinked Dextran |
| Biopolymer particles |
Crosslinked magnetic dextran nanoparticles (nanomag® -CLD -spio)
- prepared by precipitation of iron oxide in the presence of dextran
- available with particle diameters of 20 nm, 50 nm and 100 nm
- consist of about 70-90% (w/w) iron oxide in a matrix of dextran (40.000 D) in dependence on the diameter and surface modification
- differ in the size of the iron oxide domains for different diameters
- can not be separated with a conventional permanent magnet but in a high gradient magnetic field
- preferably applied for detection purposes in magnetic resonance imaging or in magneto-immuno assays
- show good specific power absorption rates for hyperthermia applications for a particle diameter of 100 nm
- designed with amino or ma
|
| Product-No. |
77-01-102, 77-01-201, 77-01-501 |
77-96-102, 77-96-201, 77-96-501 |
| Product-Name |
nanomag® -CLD -spio |
| Surface |
NH2 |
maleimide |
| Size |
100 nm , 20 nm, 50 nm |
| Solid content |
5 mg/mL |
| Quantity |
10 mL |
5 mL |
| Composition |
cross-linked dextran iron oxide composite particles |
| Polydispersity Index |
< 0.2 |
| Shape |
cluster-typed |
| Density |
1.4 g/㎤ |
| Iron Concentration |
2.4 mg/mL |
| Magnetization |
59 emu/g iron (H =1000 Oe) (100 nm)
58 emu/g iron (H =1000 Oe) (20 nm)
56 emu/g iron (H =1000 Oe) (50 nm) |
Saturation
Magnetization |
>71 emu/g iron (H > 10.000 Oe) (100 nm)
>74 emu/g iron (H > 10.000 Oe) (20 nm)
>74 emu/g iron (H > 10.000 Oe) (50 nm) |
| Coercive Field Hc |
0.147 kA/m (100 nm) , 0.100 kA/m (20 nm), 0.122 kA/m (50 nm) |
| Stable in |
aqueous buffers pH > 4 |
| Not stable in |
organic solvents, acidic solutions pH < 4 |
| Product Form |
aqueous suspension |
suspension in PBS buffer (1 mM EDTA, pH = 7.4) |
| Particles per ml |
7.5*10E12 (100 nm) , 8.0*10E14 (20 nm), 5.5*10E13 (50 nm) |
| Particles per mg |
1.5*10E12 (100 nm) , 1.6*10E14 (20 nm), 1.1*10E13 (50 nm) |
Surface Charge
Density |
10 μmol/ g iron (100 nm)
15 μmol/ g iron (20 nm)
12 μmol/ g iron (50 nm) |
n/a |
| Additional Remarks |
torage at 2 - 8°C for 6 months |
Storage at 2 - 8°C for 3 months |
