AFFINILUTE™ MIP ß-Blockers
Class-selective SPE sorbent for multi-residue extraction of ß-blockers in water and biological samples
ß-blockers, also called ß-receptor antagonists, are an important class of anti-hypertension and cardio arrhythmic drugs. For clinical, veterinary and environmental monitoring a highly selective and sensitive method for the simultaneous determination of several ß-blockers is required. Using AFFINILUTE MIP - ß-Blocker an easy, effective and selective extraction of the ß-blockers is obtained.
A broad spectrum of ß-blockers in biological samples can be extracted with the AFFINILUTE MIP-ß Blocker product e.g. atenolol, betaxolol, carazolol, pindolol, propranolol, sotalolol, timolol, metoprolol.>
Detection limits are consistent with a reliable survey of drugs of abuse. The MIP columns have a superior loading capacity compared to immuno-affinity columns. It is recommended to use MS detection for results requiring forensic validity. It is also possible to use the AFFINILUTE MIP -ß blocker columns in automated solid-phase extraction systems.
Features and Applications
At extremely low limits of detection and quantification a broad spectrum of ß-blockers in biological samples can be extracted with the AFFINILUTE MIP - ß-blocker column. AFFINILUTE MIP - ß-Blocker is class selective towards a broad range of ß-blocker e.g. atenolol, betaxolol, carazolol, pindolol, propranolol, sotalolol, timolol, metoprolol.
||AFFINILUTE MIP - ß-blockers 25 mg/ 10 mL
||AFFINILUTE MIP - ß-blockers 25 mg/ 3 mL
ß-Blockers : 베타차단제 (교감신경계의 효과기 세포에 존재한다고 하는 ß-수용체로, 이소프로텔레놀, 아드레날린 등의 ß-작용제와 특이적, 경합적, 가역적 길항을 해서, 효과기 세포특유의 생리적인 반응을 차단하는 약물)